Medical grade nitrous oxide
DSW produces medical nitrous oxide in various purities and densities, with customized packaging options to meet the needs of global customers, particularly those in the medical industry.
Medical nitrous oxide helps patients stay calm and comfortable during surgery or dental treatment. It slightly reduces awareness, making it easier to manage pain and undergo longer procedures. Today, more than 80% of medical N₂O is used in the healthcare and dental fields due to its reliable pain-relieving and sedative effects.
What Is Laughing Gas?
Nitrous oxide (chemical formula N₂O)—also called dinitrogen oxide, nitro, or medical N₂O—is a non-flammable gas with a slightly sweet odor and taste. At room temperature, it is stable and safe to handle, while at high temperatures it acts as a powerful oxidizer similar to oxygen.
Technical Specifications
- Purity: 99.9% (Medical Grade)
- CAS No.: 10102-43-9
- EINECS No.: 233-271-0
- UN No.: UN1660
- DOT Class: 2.3
- Appearance: Colourless
Nitrous Oxide Cylinder Specifications
| Specification | 10L Cylinder | 40L Cylinder |
|---|---|---|
| Outside Diameter | 140 / 152 / 159 mm | 219 mm |
| Height | 790 / 890 / 950 mm | 1,333 mm |
| Weight | 12.6 – 13.4 kg | 48 kg |
| Working Pressure | 150 BAR | 150 BAR |
| Test Pressure | 250 BAR | 250 BAR |
| Material | 37Mn Steel | 37Mn Steel |
| Wall Thickness | 4.1 – 4.4 mm | 5.7 mm |
| Standard | ISO 9809-3 | ISO 9809-3 |
| Filling Weight (N₂O) | 5 kg | 20 / 24 kg |
How to Use Medical Grade Nitrous Oxide?
Medical grade nitrous oxide should only be administered by trained healthcare professionals in a controlled environment. It is typically delivered through a face mask or nasal hood, mixed with oxygen to ensure safe breathing. The gas takes effect within minutes, helping patients relax and feel less pain during treatment. Once the procedure is complete, oxygen is given for a short time to clear the remaining gas from the body, allowing a quick recovery.
Refill cylinders are available in 1.5 L, 3 L, 10 L, 25 L, 35 L, and 50 L, based on their nominal water capacity.
Nitric Oxide Dosing Information
Usual Pediatric Dose for Respiratory Failure:
- Recommended dose: 20 ppm
- Duration of therapy: up to 14 days or until oxygen desaturation resolves
- Weaning: Down-titrate in steps, pausing several hours at each stage to monitor for hypoxemia
Comments:
- Doses above 20 ppm are not recommended
- Avoid abrupt discontinuation
Use(s): Improves oxygenation and reduces the need for extracorporeal membrane oxygenation in term and near-term neonates with hypoxic respiratory failure associated with pulmonary hypertension, alongside ventilatory support.
Applications in Medicine
Medical nitrous oxide helps reduce pain and anxiety by lowering a patient’s level of consciousness, making it easier to undergo longer or more uncomfortable procedures. It is commonly used in both adults and children for:
- General anaesthesia – usually as a supplement to other anaesthetic gases or intravenous agents.
- Pain relief – used with oxygen to provide analgesia during procedures such as dental treatments, childbirth, and fracture management.
- Conscious sedation – helps calm anxious or apprehensive patients while maintaining communication and responsiveness.
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